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Concomitant use of paroxetine and maois is contraindicated because of the risk of serotonin syndrome see section 4.

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Seek medical attention right away if you have symptoms such asagitationhallucinationsmuscle stiffnesstwitchingloss of coordinationdizzinesswarmth or tingly feelingnauseavomitingdiarrheafeversweatingtremorsracing heartbeatsor a seizureconvulsions

Taking paroxetine during pregnancy may cause serious lung problemsa heart defector other complications in the babyHoweveryou may have a relapse of depression or other treated condition if you stop taking your antidepressantTell your doctor right away if you become pregnantDo not start or stop taking paroxetine during pregnancy without your doctor’s advice.

PediatricSafety and efficacy not established GeriatricCaution should be used in the elderly because paroxetine is the most sedating and anticholinergic of the selective serotonin reuptake inhibitors The elderly are prone to SSRI/SNRI-induced hyponatremiamonitor closely.

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