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A patient Medication Guide is available for Reglan InjectionThe prescriber or health professional should instruct patientstheir familiesand their caregivers to read the Medication Guide and should assist them in understanding its contentsPatients should be given the opportunity to discuss the contents of the Medication Guide and to obtain answers to any questions they may haveRefer to accompanying Medication Guide.

Metoclopramide is contraindicated in patients with pheochromocytoma because the drug may cause a hypertensive crisisprobably due to release of catecholamines from the tumorSuch hypertensive crises may be controlled by phentolamine.

Giving a promotility drug such as metoclopramide theoretically could put increased pressure on suture lines following a gut anastomosis or closureThis possibility should be considered and weighed when deciding whether to use metoclopramide or nasogastric suction in the prevention of postoperative nausea and vomiting.

Mental depression has occurred in patients with and without prior history of depressionSymptoms have ranged from mild to severe and have included suicidal ideation and suicideMetoclopramide should be given to patients with a prior history of depression only if the expected benefits outweigh the potential risks.

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